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Livres
Articles (36)
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Evaluation of drug–drug interactions with fesoterodine

Bimal Malhotra, Richard Sachse, Nolan Wood

Journal:

European Journal of Clinical Pharmacology

Année:

2009

Langue:

english

Fichier:

PDF, 315 KB

english, 2009

Modeling dose-response relationships of the effects of fesoterodine in patients with overactive bladder

Linda Cardozo, Vik Khullar, Ahmed El-Tahtawy, Zhonghong Guan, Bimal Malhotra, David Staskin

Journal:

BMC Urology

Année:

2010

Langue:

english

Fichier:

PDF, 1.03 MB

english, 2010

The pharmacokinetic profile of fesoterodine 8

Bimal K. Malhotra, Penelope H. Crownover, Robert LaBadie, Paul Glue, Scott A. MacDiarmid

Journal:

European Journal of Clinical Pharmacology

Année:

2010

Langue:

english

Fichier:

PDF, 137 KB

english, 2010

The effects of reformulation: Improved therapeutic index

Scott MacDiarmid, Bobby W. Sandage, Bimal K. Malhotra

Journal:

Current Urology Reports

Année:

2008

Langue:

english

Fichier:

PDF, 287 KB

english, 2008

Comparison of pharmacokinetic variability of fesoterodine vs. tolterodine extended release in cytochrome P450 2D6 extensive and poor metabolizers

Bimal Malhotra, Edress Darsey, Penelope Crownover, Juanzhi Fang, Paul Glue

Journal:

British Journal of Clinical Pharmacology

Année:

2011

Langue:

english

Fichier:

PDF, 1.29 MB

english, 2011

A comprehensive non-clinical evaluation of the CNS penetration potential of antimuscarinic agents for the treatment of overactive bladder

Ernesto Callegari, Bimal Malhotra, Peter J. Bungay, Rob Webster, Katherine S. Fenner, Sarah Kempshall, Jennifer L. LaPerle, Martin C. Michel, Gary G. Kay

Journal:

British Journal of Clinical Pharmacology

Année:

2011

Langue:

english

Fichier:

PDF, 1.38 MB

english, 2011

Effects of fesoterodine on the pharmacokinetics and pharmacodynamics of warfarin in healthy volunteers

Bimal Malhotra, Christine Alvey, Jason Gong, Xiaoxi Li, Gregory Duczynski, Kuan Gandelman

Journal:

British Journal of Clinical Pharmacology

Année:

2011

Langue:

english

Fichier:

PDF, 949 KB

english, 2011

Effects of the moderate CYP3A4 inhibitor, fluconazole, on the pharmacokinetics of fesoterodine in healthy subjects

Bimal Malhotra, Maurice Dickins, Christine Alvey, Zhanna Jumadilova, Xiaoxi Li, Gregory Duczynski, Kuan Gandelman

Journal:

British Journal of Clinical Pharmacology

Année:

2011

Langue:

english

Fichier:

PDF, 829 KB

english, 2011

Investigation of the Distribution of EAB 515 to Cortical ECF and CSF in Freely Moving Rats Utilizing Microdialysis

Bimal K. Malhotra, Michel Lemaire, Ronald J. Sawchuk

Journal:

Pharmaceutical Research

Année:

1994

Fichier:

PDF, 1.65 MB

1994

A meta-analysis of the placebo response in antimuscarinic drug trials for overactive bladder

Soyon Lee, Bimal Malhotra, Dana Creanga, Martin Carlsson, Paul Glue

Journal:

BMC Medical Research Methodology

Année:

2009

Langue:

english

Fichier:

PDF, 336 KB

english, 2009

Dose-escalating study of the pharmacokinetics and tolerability of fesoterodine in children with overactive bladder

Bimal Malhotra, Ahmed El-Tahtawy, Ellen Q. Wang, Amanda Darekar, Nandini Cossons, Tim J. Crook, David Scholfield, Pramod Reddy

Journal:

Journal of Pediatric Urology

Année:

2012

Langue:

english

Fichier:

PDF, 382 KB

english, 2012

Effects of Food on the Clinical Pharmacokinetics of Anticancer Agents

Dr Brahma N. Singh, Bimal K. Malhotra

Journal:

Clinical Pharmacokinetics

Année:

2004

Langue:

english

Fichier:

PDF, 240 KB

english, 2004

ASSESSMENT OF CENTRAL NERVOUS SYSTEM ACCESS OF A NEW ANTIMUSCARINIC DRUG, FESOTERODINE

Kay, Gary, Malhotra, Bimal, Michel, Martin C

Journal:

The Journal of Urology

Année:

2009

Langue:

english

Fichier:

PDF, 130 KB

english, 2009

Population Pharmacokinetics of Atorvastatin and Its Active Metabolites in Children and Adolescents With Heterozygous Familial Hypercholesterolemia: Selective Use of Informative Prior Distributions from Adults

Knebel, William, Gastonguay, Marc R., Malhotra, Bimal, El-Tahtawy, Ahmed, Jen, Frank, Gandelman, Kuan

Journal:

Journal of Clinical Pharmacology

Année:

2013

Langue:

english

Fichier:

PDF, 1.70 MB

english, 2013

Modeling the Route of Administration-Based Enhancement in the Brain Delivery of EAB 515, Studied by Microdialysis

Malhotra, Bimal, Brundage, Richard, Lemaire, Michel, Sawchuk, Ronald

Journal:

Journal of Drug Targeting

Année:

1997

Langue:

english

Fichier:

PDF, 762 KB

english, 1997

Assessment of the Effects of Renal Impairment on the Pharmacokinetic Profile of Fesoterodine

Malhotra, Bimal, Gandelman, Kuan, Sachse, Richard, Wood, Nolan

Journal:

Journal of Clinical Pharmacology

Année:

2009

Langue:

english

Fichier:

PDF, 190 KB

english, 2009

Effects of Hepatic Dysfunction on the Single-Dose Pharmacokinetics of Fesoterodine

de Mey, Christian, Mateva, Lyudmila, Krastev, Zahariy, Sachse, Richard, Wood, Nolan, Malhotra, Bimal

Journal:

Journal of Clinical Pharmacology

Année:

2011

Langue:

english

Fichier:

PDF, 330 KB

english, 2011

Population pharmacokinetics of the 5-hydroxymethyl metabolite of tolterodine after administration of fesoterodine sustained release tablet in western and east Asian populations

Oishi, Masayo, Tomono, Yoshiro, Yamagami, Hidetomi, Malhotra, Bimal

Journal:

Journal of Clinical Pharmacology

Année:

2014

Langue:

english

Fichier:

PDF, 477 KB

english, 2014

Effects of Ethanol on the Pharmacokinetics of Extended-Release Oxycodone with Sequestered Naltrexone (ALO-02)

Malhotra, Bimal K., Matschke, Kyle, Wang, Qiang, Bramson, Candace, Salageanu, Joanne

Journal:

Clinical Drug Investigation

Année:

2015

Langue:

english

Fichier:

PDF, 377 KB

english, 2015

Pharmacoscintigraphy studies to assess the feasibility of a controlled release formulation of ziprasidone

Thombre, Avinash G., Shamblin, Sheri L., Malhotra, Bimal K., Connor, Alyson L., Wilding, Ian R., Caldwell, W. Brett

Journal:

Journal of Controlled Release

Année:

2015

Langue:

english

Fichier:

PDF, 524 KB

english, 2015

Evaluation of Cognitive Function in Healthy Older Subjects Treated with Fesoterodine

Kay, Gary G., Maruff, Paul, Scholfield, David, Malhotra, Bimal, Whelan, Laurence, Darekar, Amanda, Martire, Diane L.

Journal:

Postgraduate Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 720 KB

english, 2012

Intravenous abuse potential study of oxycodone alone or in combination with naltrexone in nondependent recreational opioid users

Backonja, Miroslav, Webster, Lynn R., Setnik, Beatrice, Bass, Almasa, Sommerville, Kenneth W., Matschke, Kyle, Malhotra, Bimal K., Wolfram, Gernot

Journal:

The American Journal of Drug and Alcohol Abuse

Année:

2016

Langue:

english

Fichier:

PDF, 1.24 MB

english, 2016

Pharmacokinetics of Tolterodine in Japanese and Koreans: Physiological and Stochastic Assessment of Ethnic Differences

Oishi, Masayo, Chiba, Koji, Malhotra, Bimal, Suwa, Toshio

Journal:

Drug Metabolism and Pharmacokinetics

Année:

2011

Langue:

english

Fichier:

PDF, 222 KB

english, 2011

Safety of intravenous nitroglycerin after administration of sildenafil citrate to men with coronary artery disease: A double-blind, placebo-controlled, randomized, crossover trial*

Parker, John D., Bart, Bradley A., Webb, David J., Koren, Michael J., Siegel, Richard L., Wang, Hao, Malhotra, Bimal, Jen, Frank, Glue, Paul

Journal:

Critical Care Medicine

Année:

2007

Langue:

english

Fichier:

PDF, 405 KB

english, 2007

Intranasal administration of crushed ALO-02 (extended-release oxycodone with sequestered naltrexone): A randomized, controlled abuse-potential study in nondependent recreational opioid users

Setnik, Beatrice, Bramson, Candace, Bass, Almasa, Levy-Cooperman, Naama, Malhotra, Bimal, Matschke, Kyle, Sommerville, Kenneth W., Wolfram, Gernot, Geoffroy, Pierre

Journal:

Journal of Clinical Pharmacology

Année:

2015

Langue:

english

Fichier:

PDF, 405 KB

english, 2015

Effect of food on the pharmacokinetics of oxycodone and naltrexone from ALO-02, an extended release formulation of oxycodone with sequestered naltrexone

Gandelman, Kuan, Lamson, Michael, Salageanu, Joanne, Bramson, Candace, Matschke, Kyle, Malhotra, Bimal

Journal:

Clinical Pharmacology in Drug Development

Année:

2015

Langue:

english

Fichier:

PDF, 208 KB

english, 2015

Single- and multiple-dose study to evaluate pharmacokinetics, safety and tolerability in healthy volunteers: A comparison of extended-release oxycodone with sequestered naltrexone 40 mg twice daily to oxycontin 40 mg twice daily and extended-release oxyco

Gandelman, Kuan, Lamson, Michael, Bramson, Candace, Matschke, Kyle, Salageanu, Joanne, Malhotra, Bimal

Journal:

Clinical Pharmacology in Drug Development

Année:

2015

Langue:

english

Fichier:

PDF, 446 KB

english, 2015

A randomized double-blind, placebo-controlled efficacy and safety study of ALO-02 (extended-release oxycodone surrounding sequestered naltrexone) for moderate-to-severe chronic low back pain treatment

Rauck, Richard L., Hale, Martin E., Bass, Almasa, Bramson, Candace, Pixton, Glenn, Wilson, Jacquelyn G., Setnik, Beatrice, Meisner, Paul, Sommerville, Kenneth W., Malhotra, Bimal K., Wolfram, Gernot

Journal:

PAIN®

Année:

2015

Langue:

english

Fichier:

PDF, 268 KB

english, 2015

Abuse Potential Study of ALO-02 (Extended-Release Oxycodone Surrounding Sequestered Naltrexone) Compared with Immediate-Release Oxycodone Administered Orally to Nondependent Recreational Opioid Users

Stenik, Beatrice, Bass, Almasa, Bramson, Candace, Levy-Cooperman, Naama, Malhotra, Bimal, Matschke, Kyle, Geoffroy, Pierre, Sommerville, Kenneth W., Wolfram, Gernot

Journal:

Pain Medicine

Année:

2016

Langue:

english

Fichier:

PDF, 300 KB

english, 2016

Oral Bioavailability and Disposition of [ 14 C]Omapatrilat in Healthy Subjects

Malhotra, Bimal K., Iyer, Ramaswamy A., Soucek, Kathy M., Behr, Douglas, Liao, Wei-chi, Mitroka, James G., Kaul, Sanjeev, Cohen, Marvin B., Knupp, Catherine A.

Journal:

Journal of Clinical Pharmacology

Année:

2001

Langue:

english

Fichier:

PDF, 117 KB

english, 2001

Physiological based pharmacokinetic modeling to estimate in vivo Ki of ketoconazole on renal P-gp using human drug-drug interaction study result of fesoterodine and ketoconazole

Oishi, Masayo, Takano, Yuma, Torita, Yutaka, Malhotra, Bimal, Chiba, Koji

Journal:

Drug Metabolism and Pharmacokinetics

Année:

2017

Langue:

english

Fichier:

PDF, 1.02 MB

english, 2017

Effects of intravenous oxycodone alone or in combination with naltrexone on measures of respiratory depression: a randomized placebo-controlled study

Bass, Almasa, Webster, Lynn R., Matschke, Kyle T., Malhotra, Bimal K., Wolfram, Gernot

Journal:

Therapeutic Advances in Drug Safety

Année:

2019

Fichier:

PDF, 293 KB

2019

Physiologically Based Pharmacokinetic Modeling Suggests Limited Drug‐Drug Interaction for Fesoterodine When Coadministered With Mirabegron

Lin, Jian, Goosen, Theunis C., Tse, Susanna, Yamagami, Hidetomi, Malhotra, Bimal

Journal:

Journal of Clinical Pharmacology

Année:

2019

Langue:

english

Fichier:

PDF, 341 KB

english, 2019

Physiologically Based Pharmacokinetic Modeling Suggests Limited Drug‐Drug Interaction for Fesoterodine When Coadministered With Mirabegron

Lin, Jian, Goosen, Theunis C., Tse, Susanna, Yamagami, Hidetomi, Malhotra, Bimal

Journal:

Journal of Clinical Pharmacology

Année:

2019

Fichier:

PDF, 341 KB

2019

P190 - The effect of CYP2C9 and CYP2C19 genotype on the pharmacokinetics of PF 04965842, A JAK1 inhibitor in clinical development

Dowty, Martin, Yang, Xin, Lin, Jian, Bauman, Jonathan, Doran, Angela, Goosen, Theunis, Wood, Linda, Johnson, Jillian, Banfield, Christopher, Gupta, Pankaj, Malhotra, Bimal

Journal:

Drug Metabolism and Pharmacokinetics

Année:

2020

Fichier:

PDF, 46 KB

2020

15433 Assessment of cytochrome P450 3A inhibition and induction of abrocitinib: Midazolam drug-drug interaction (DDI) study and oral contraceptive DDI study

Wang, Xiaoxing, Huh, Yeamin, Curto, Madelyn, Chan, Gary, Dowty, Martin E., O'Gorman, Melissa, Tripathy, Sakambari, Malhotra, Bimal, Gupta, Pankaj

Journal:

Journal of the American Academy of Dermatology

Année:

2020

Fichier:

PDF, 147 KB

2020